✍️✍️✍️ Cerebral Hemorrhage Latin America Case Study

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Cerebral Hemorrhage Latin America Case Study



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Case Studies – Stroke

Findings: Of cases of stroke identified, were incident. The overall age-adjusted incidence rate of first-ever stroke was The incidence rates per , according to pathological type were: infarcts The 30 day and 6-month case-fatality rates were Interpretation: Our results show incidence rates of stroke similar to those reported in other community studies. Although the proportion of intracerebral haemorrhages was higher than reported in previous studies, the overall incidence was not, which could indicate a slightly lower incidence of ischaemic strokes in this population than in other countries.

The prognosis was similar to that found in other population-based studies. Abstract Background: The epidemiology of stroke in Latin-American populations and variation of subtypes between communities are unclear. While the volume of COVIDrelated case studies continues to grow, previous work examining related viruses suggests potential mechanisms through which the novel coronavirus may impact the CNS and result in neurological complications. Namely, animal studies examining the SARS-CoV have implicated the angiotensin-converting-enzyme-2 receptor as a mediator of coronavirus-related neuronal damage and have shown that SARS-CoV can infect cerebrovascular endothelium and brain parenchyma, the latter predominantly in the medial temporal lobe, resulting in apoptosis and necrosis.

Additionally, studies have demonstrated an increase in cytokine serum levels as a result of SARS-CoV infection, consistent with the notion that cytokine overproduction and toxicity may be a relevant potential mechanism of neurologic injury, paralleling a known pathway of pulmonary injury. Early reports suggest COVID may be associated with severe neurologic complications, and several plausible mechanisms exist to account for these observations.

A heightened awareness of the potential for neurologic involvement and further investigation into the relevant pathophysiology will be necessary to understand and ultimately mitigate SARS-CoVassociated neurologic injury. Keywords: Cerebrovascular stroke; Coronavirus; Inflammation; Neurology.

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